Cart
sales@molnova.com
HIF-1 alpha (556-574) TFA
CAS No. ——
HIF-1 alpha (556-574) TFA( —— )
Catalog No. M30245 CAS No. ——
This is a hypoxia-inducible factor-1 (HIF-1 a) 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1 subunit is stabilized in response to a lack of oxygen. This part of HIF-1 binds to the von Hippel-Lindau factor (VHL) an E3 ubiquitin ligase, and the proline 564 is absolutely critical to the binding process.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
Biological Information
-
Product NameHIF-1 alpha (556-574) TFA
-
NoteResearch use only, not for human use.
-
Brief DescriptionThis is a hypoxia-inducible factor-1 (HIF-1 a) 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1 subunit is stabilized in response to a lack of oxygen. This part of HIF-1 binds to the von Hippel-Lindau factor (VHL) an E3 ubiquitin ligase, and the proline 564 is absolutely critical to the binding process.
-
DescriptionThis is a hypoxia-inducible factor-1 (HIF-1 a) 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1 subunit is stabilized in response to a lack of oxygen. This part of HIF-1 binds to the von Hippel-Lindau factor (VHL) an E3 ubiquitin ligase, and the proline 564 is absolutely critical to the binding process.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number——
-
Formula Weight2368.62
-
Molecular FormulaC103H151D2F3N20O36S2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical NameSequence:{Asp}{Leu}{Asp}{Leu}{Glu}{Met}{Leu}{Ala}{Pro}{Tyr}{Ile}{Pro}{Met}{Asp}{Asp}{Asp}{Phe}{Gln}{Leu}
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
Ehrismann D, et al. Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assay. Biochem J. 2007 Jan 1;401(1):227-34.
molnova catalog
related products
-
N-Acetyl-DL-tryptoph...
N-Acetyl-tryptophan was study for its possible anti-?inflammatory and antinociceptive activities from the extraction of a Turkish plant Salsola grandis.
-
6-Bromoindole-3-carb...
6-Bromoindole-3-carboxylic acid is a marine derived natural products found in Pseudosuberites hyalinus.
-
NAI-N3
NAI-N3 is a RNA acylation reagent that enables RNA purification. NAI-N3 is a dual-function SHAPE (selective 2-hydroxyl acylation and profiling experiment) probe (RNA structure probe and enrichment).
